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Projektnews Rosetta@home: Another publication in Nature describing the first de novo designed proteins with anti-cancer activity
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A report was published in Nature last week describing the first de novo designed proteins with anti-cancer activity.
These compact molecules were designed to stimulate the same receptors as IL-2, a powerful immunotherapeutic drug, while avoiding unwanted off-target receptor interactions. We believe this is just the first of many computer-generated cancer drugs with enhanced specificity and potency.
R@h participants provided computing for forward folding experiments used in this study which helped validate designs. We'd like to congratulate and thank all R@h volunteers who contributed to this work! Thank you!
Read the full article here: https://www.nature.com/articles/s41586-018-0830-7 (PDF)
Weiterlesen auf der Projekthomepage
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